Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
This gene encodes a member of the RRM family of RNA-binding proteins. The RRM domain is between 80-100 amino acids in length and family members contain one to four copies of the domain. The RRM domain consists of two short stretches of conserved sequence called RNP1 and RNP2, as well as a few highly conserved hydrophobic residues. The protein encoded by this gene has a single, putative RRM domain in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: Heart and RRM expressed sequence; Hermes; RBP-MS; RNA-binding protein with multiple splicing
Gene Aliases: HERMES; RBPMS
UniProt ID: (Human) Q93062
Entrez Gene ID: (Human) 11030
Molecular Function: RNA splicing factor