This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1.
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cell cycle regulatory protein; Chromosome condensation protein 1; guanine nucleotide-releasing protein; Regulator of chromosome condensation; SNHG3-RCC1 readthrough
Gene Aliases: 4931417M11Rik; AI326872; CHC1; RCC1; RCC1-I; SNHG3-RCC1