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Invitrogen
RCC2 Polyclonal Antibody
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FIGURE: 1 / 2
RCC2 Antibody (PA5-99702) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded RCC2 in human spleen tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with RCC2 polyclonal antibody (Product # PA5-99702) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-99702
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RCC2(Accession Q9P258), corresponding to amino acid residues C437-E487.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RCC2.
Target Information
Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory sperm binding protein; Protein RCC2; RCC1-like protein TD-60; regulator of chromosome condensation 2; Telophase disk protein of 60 kDa
Gene Aliases: 2610510H01Rik; 2610529N02Rik; AA536646; AA675016; KIAA1470; mKIAA1470; RCC2; RGD1309986; TD-60; TD60
UniProt ID: (Human) Q9P258, (Mouse) Q8BK67
Entrez Gene ID: (Human) 55920, (Mouse) 108911, (Rat) 298594
mitotic cell cycle
endosome organization
cell cycle
mitotic nuclear division
integrin-mediated signaling pathway
regulation of fibroblast migration
positive regulation of G2/M transition of mitotic cell cycle
regulation of cell migration
negative regulation of GTPase activity
establishment of protein localization
focal adhesion assembly
cell division
negative regulation of focal adhesion assembly
positive regulation of attachment of spindle microtubules to kinetochore
chromosome passenger complex localization to kinetochore
activation of GTPase activity
negative regulation of substrate adhesion-dependent cell spreading
regulation of ruffle assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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