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Proteintech
RDH5 Polyclonal Antibody
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Product Details
13140-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RDH5 Fusion Protein Ag3784
Conjugate
Form
Liquid
Concentration
500 µg/mL
Amount
75 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Aliquoting is unnecessary for -20°C storage.
Target Information
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 11-cis RDH; 11-cis retinol dehydrogenase; 11-cis RoDH; 9-cis retinol dehydrogenase; 9-cis-retinol dehydrogenase; 9-cis-retinol specific dehydrogenase; 9cRDH; Cis-retinol dehydrogenase; FLJ39337; FLJ97089; rdh5; retinol dehydrogenase 1; Retinol dehydrogenase 5; retinol dehydrogenase 5 (11-cis and 9-cis); retinol dehydrogenase 5 (11-cis/9-cis); retinol dehydrogenase type 5; Short chain dehydrogenase/reductase family 9C member 5; unnamed protein product
Gene Aliases: 9-cis; 9cRDH; AI987873; cRDH; HSD17B9; rdh; RDH1; RDH4; RDH5; SDR9C5
UniProt ID: (Human) Q92781, (Mouse) O55240
Entrez Gene ID: (Human) 5959, (Mouse) 19682, (Rat) 366791
retinol dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
protein homodimerization activity
androsterone dehydrogenase activity
androstan-3-alpha,17-beta-diol dehydrogenase activity
11-cis-retinol dehydrogenase (NAD+) activity
molecular_function
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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