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Proteintech
REDD1 Polyclonal Antibody, CoraLite® Plus 488
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FIGURE: 1 / 1
REDD1 Antibody (CL488-10638) in Flow
1x10^6 K-562 cells were intracellularly stained with 0.8 µg Coralite® Plus 488 Redd1 Specific Polyclonal Antibody (CL488-10638) (red), or 0.8 µg CoraLite® Plus 488-conjugated Rabbit IgG control Rabbit PolyAb (CL488-30000) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL488-10638
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
REDD1 specific fusion protein Ag0965
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MPSLWDRFS SSSTSSSPSS LPRTPTPDRP PRSAWGSATR EEGFDRSTSL ESSDCESLDS SNSGFGPEED TAYLDGVSLP DFELLSDPED EHLCANLMQL LQESLAQARL GSRRPARLLM PSQLVSQVGK ELLRLAYSEP CGLRGALLDV CVEQGKSCHS VGQLALDPSL VPTFQLTLVL RLDSRLWPKI QGLFSSANSP FLPGFSQSLT LSTGFRVIKK KLYSSEQLLI EEC
Target Information
DDIT4 gene ontology annotations related to this gene include cellular response to dexamethasone stimulus; intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; negative regulation of glycolytic process; negative regulation of TOR signaling; protein-containing complex disassembly; reactive oxygen species metabolic process; response to hypoxia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dexamethasone-induced gene 2 protein; DNA damage-inducible transcript 4 protein; DNA-damage-inducible transcript 4; DNA-damage-inducible transcript 4 protein; HIF-1 responsive protein RTP801; HIF-1 responsive RTP801; Protein regulated in development and DNA damage response 1; REDD-1; RP11-442H21.1
Gene Aliases: 5830413E08Rik; AA415483; DDIT4; Dig2; REDD-1; REDD1; RTP801
UniProt ID: (Human) Q9NX09, (Mouse) Q9D3F7
Entrez Gene ID: (Human) 54541, (Mouse) 74747
response to hypoxia
neuron migration
apoptotic process
brain development
cell proliferation
negative regulation of signal transduction
negative regulation of peptidyl-threonine phosphorylation
neuron differentiation
negative regulation of TOR signaling
negative regulation of peptidyl-serine phosphorylation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
protein complex disassembly
negative regulation of glycolytic process
neurotrophin TRK receptor signaling pathway
defense response to virus
reactive oxygen species metabolic process
positive regulation of neuron death
negative regulation of intracellular signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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