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Proteintech
REEP5 Polyclonal Antibody
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FIGURE: 1 / 11
REEP5 Antibody (14643-1-AP) in ICC/IF
Immunofluorescent analysis of (4% PFA) fixed A549 cells using REEP5 antibody (Product # 14643-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). F-actin is stained using CL555-phalloidin (red) and DNA is stained by DAPI (blue).
Product Details
14643-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
REEP5 Fusion Protein Ag6229 (1-189 aa encoded by BC065926)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSAAMRERF DRFLHEKNCM TDLLAKLEAK TGVNRSFIAL GVIGLVALYL VFGYGASLLC NLIGFGYPAY ISIKAIESPN KEDDTQWLTY WVVYGVFSIA EFFSDIFLSW FPFYYMLKCG FLLWCMAPSP SNGAELLYKR IIRPFFLKHE SQMDSVVKDL KDKAKETADA ITKEAKKATV NLLGEEKKST (1-189 aa encoded by BC065926)
Target Information
REEP5 (receptor expression-enhancing protein 5), also known as C5orf18, DP1, TB2 or D5S346, is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the parm of chromosome 5 leads to cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: deleted in polyposis 1; GP106; polyposis coli region hypothetical protein DP1; Polyposis locus protein 1; Polyposis locus protein 1 homolog; Protein TB2; protein TB2 homolog; receptor expression enhancing protein 5; Receptor expression-enhancing protein 5
Gene Aliases: AI324241; AU022809; AW495741; C5orf18; D5S346; DP1; DP1/TB2; R74856; REEP5; TB2; TB2/DP1; Yip2e; YOP1
UniProt ID: (Human) Q00765, (Rat) B2RZ37
Entrez Gene ID: (Human) 7905, (Rat) 364838, (Mouse) 13476
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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