|Tested species reactivity||Human, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (26 GEEPQRELPSARIRC 40~^) of REG3A protein.|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||2.5-5 µg/ml|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
REG3A, also known as Regenerating islet-derived protein 3 alpha, Reg III-alpha, and pancreatitis associated protein (PAP), is a 174 amino acid containing stress protein involved in the control of bacterial proliferation. REG3A is generally found in the apical region of pancreatic acinar cells and appears in pancreatic juice after induction of pancreatic inflammation. It has a possible role in inducing new pancreatic islets development. REG3A belongs to the Reg-related family with a C-type lectin domain and is constitutively expressed in intestine while low expression is found in healthy pancreas. Overexpression of REG3A is seen during the acute phase of pancreatitis and in some patients with chronic pancreatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.