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          • Primary Antibodies ›
          • UPF2 Antibodies

          Bethyl Laboratories

          RENT2 Polyclonal Antibody

          View all (5) UPF2 antibodies

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          Cite RENT2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          RENT2 Antibody in Western Blot (WB)
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          RENT2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          RENT2 Antibody (A303-929A) in WB

          Detection of human RENT2 by western blot. Samples: Whole cell lysate from HEK293T (15 and 50 µg), HeLa (50 µg), and Jurkat (50 µg) cells. Antibodies: Affinity purified rabbit anti-RENT2 antibody (Product # A303-929A) (lot A303-929A-1) used for WB at 0.4 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RENT2 Antibody in Western Blot (WB)
          RENT2 Antibody in Western Blot (WB)
          RENT2 Antibody in Immunoprecipitation (IP)
          RENT2 Polyclonal Antibody

          Product Details

          A303-929A

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:5,000
          -

          Immunoprecipitation (IP)

          2-10 µg/mg lysate
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Region between residue 1 and 50 of Human Regulator of Nonsense Transcripts 2.
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          tris citrate/phosphate, pH 7-8

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          The recommended shelf life for this product is 1 year from date of receipt.

          Target Information

          This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FRS2/UPF2/LEMD3 fusion; hUpf2; involved in NMD pathway; LEMD3/UPF2 fusion; nonsense mRNA reducing factor 2; Regulator of nonsense transcripts 2; smg-3 homolog, nonsense mediated mRNA decay factor; unnamed protein product; Up-frameshift suppressor 2 homolog; Upf2; UPF2 regulator of nonsense transcripts homolog; yeast Upf2p homolog

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          Gene Aliases: HUPF2; KIAA1408; RENT2; smg-3; UPF2

          View more View less

          UniProt ID: (Human) Q9HAU5, (Mouse) A2AT37

          View more View less

          Entrez Gene ID: (Human) 26019, (Mouse) 326622

          View more View less

          Function(s)
          RNA binding protein binding telomeric DNA binding RNA metabolism protein nucleic acid metabolism protein
          Process(es)
          nuclear-transcribed mRNA catabolic process, nonsense-mediated decay liver development mRNA export from nucleus organ regeneration response to unfolded protein
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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