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REQUIEM Polyclonal Antibody
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Product Details
600-401-DX7
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-REQUIEM antibody was prepared from whole rabbit serum produced by repeated immunizations with an 18 amino acid synthetic peptide near the C-terminus of human Requiem.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apoptosis response zinc finger protein; BAF45D; BRG1-associated factor 45D; D4, zinc and double PHD fingers family 2; neuro-d4/requiem; Protein requiem; requiem; requiem, apoptosis response zinc finger; unnamed protein product; Zinc finger protein ubi-d4; zinc finger; contains one C2H2 and two C4HC3
Gene Aliases: 2210010M07Rik; BAF45D; CSS7; DPF2; REQ; SMARCG2; ubi-d4; UBID4
UniProt ID: (Human) Q92785, (Mouse) Q61103
Entrez Gene ID: (Human) 5977, (Mouse) 19708
negative regulation of transcription from RNA polymerase II promoter
chromatin organization
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
apoptotic process
nervous system development
regulation of mitotic metaphase/anaphase transition
regulation of G0 to G1 transition
apoptotic signaling pathway
positive regulation of stem cell population maintenance
negative regulation of myeloid progenitor cell differentiation
regulation of G1/S transition of mitotic cell cycle
positive regulation of double-strand break repair
regulation of nucleotide-excision repair
transcription, DNA-templated
regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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