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Invitrogen
RFC2 Polyclonal Antibody
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FIGURE: 1 / 1
RFC2 Antibody (PA5-93246) in WB
Western blot analysis of RFC2 in extracts of various cell lines. Samples were incubated with RFC2 Polyclonal antibody (Product # PA5-93246) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
Product Details
PA5-93246
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 38-297 of human RFC2 (NP_8521361)
Conjugate
Form
Liquid
Concentration
1.1 mg/mL
Amount
110 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: WVEKYRPVKL NEIVGNEDTV SRLEVFAREG NVPNIIIAGP PGTGKTTSIL CLARALLGPA LKDAMLELNA SNDRGIDVVR NKIKMFAQQK VTLPKGRHKI IILDEADSMT DGAQQALRRT MEIYSKTTRF ALACNASDKI IEPIQSRCAV LRYTKLTDAQ ILTRLMNVIE KERVPYTDDG LEAIIFTAQG DMRQALNNLQ STFSGFGFIN SENVFKVCDE PHPLLVKEMI QHCVNANIDE AYKILAHLWH LGYSPEDIIG; Positive Samples: LO2, 22Rv1, Mouse spleen; Cellular Location: Nucleus
Target Information
This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A1 40 kDa subunit; Activator 1 40 kDa subunit; Activator 1 subunit 2; MGC3665; replication factor C (activator 1) 2, 40kDa; Replication factor C 40 kDa subunit; Replication factor C subunit 2; replication factor C, 40 kDa; RF-C 40 kDa subunit; RFC40
Gene Aliases: 2610008M13Rik; 40kDa; AI326953; Recc2; RFC2; RFC40
UniProt ID: (Human) P35250, (Mouse) Q9WUK4
Entrez Gene ID: (Human) 5982, (Mouse) 19718
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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