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Product Details
11814-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Full length RFC3 Fusion Protein Ag2269
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 38 kD subunit. This subunit is essential for the interaction between the 140 kD subunit and the core complex that consists of the 36, 37, and 40 kD subunits. Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A1 38 kDa subunit; Activator 1 38 kDa subunit; Activator 1 subunit 3; DNA-binding; MGC5276; Polymorphism; replication factor C (activator 1) 3, 38kDa; replication factor C 3; Replication factor C 38 kDa subunit; Replication factor C subunit 3; replication factor C, 38 kDa; RF-C 38 kDa subunit; RFC, 38 kD subunit; RFC38
Gene Aliases: 2810416I22Rik; 38kDa; AU022547; Recc3; RFC3; RFC38
UniProt ID: (Human) P40938, (Mouse) Q8R323
Entrez Gene ID: (Human) 5983, (Rat) 288414, (Mouse) 69263
telomere maintenance via recombination
DNA synthesis involved in DNA repair
DNA replication
DNA strand elongation involved in DNA replication
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
translesion synthesis
nucleotide-excision repair, DNA incision
error-prone translesion synthesis
DNA damage response, detection of DNA damage
response to organophosphorus
error-free translesion synthesis
positive regulation of DNA-directed DNA polymerase activity
regulation of signal transduction by p53 class mediator
DNA-dependent DNA replication
biological_process
Performance Guarantee
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