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Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
RFPL1, RFPL2 and RFPL3 (ret finger protein-like 1, 2 and 3, respectively), exist as a cluster of genes mapping to human chromosome 22q12.2-q13.3, sharing 95%-96% identity. RFPL1, 2 and 3, are thought to contribute to neocortex organization and size in primates, and show high expression in fetal neocortex as well as embryonic stem-cell neurogenesis. Each of the three RFPL genes encodes two exons giving rise to a putative RING-like motifs and B30-2 domains. RFPL2, or RNF79, is 378 amino acids long and is also highly expressed in prostate with lower expression in fetal kidney and fetal liver. As a result of alternative splicing, two isoforms of RFPL2 exist.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ret finger protein-like 2; RING finger protein 79
Gene Aliases: RFPL2; RNF79
UniProt ID: (Human) O75678
Entrez Gene ID: (Human) 10739
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