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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 21 and 117 of RFX1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28876 targets RFX1 in WB applications and shows reactivity with Human samples.
The PA5-28876 immunogen is a synthetic peptide corresponding to a region within amino acids 21 and 117 of RFX1.
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
EFC; enhancer factor C; MHC class II regulatory factor RFX; regulatory factor X 1; regulatory factor X, 1 (influences HLA class II expression); RFX; trans-acting regulatory factor 1; transcription factor RFX1
EFC; RFX; RFX1