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Proteintech
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Sequence of this protein is as follows: VLPKDKLISL CQCDPILRWM RSCDHILYQA LVEILIPDVL RPVPSTLTQA IRNFAKSLEG WLTNAMSDFP QQVIQTKVGV VSAFAQTLRR YTSLNHLAQA ARAVLQNTSQ INQMLSDLNR VDFANVQEQA SWVCQCEESV VQRLEQDFKL TLQQQSSLDQ WASWLDSVVT QVLKQHAGSP SFPKAAQQFL LKWSFYSSMV IRDLTLRSAA SFGSFHLIRL LYDEYMFYLV EHRVAEATGE TPIAVMGEFN DLASLSLTLL DKDDMGDEQR GSEAGPDARS LGEPLVKRER SDPNHSLQGI
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA binding protein RFX2; DNA-binding protein RFX2; FLJ14226; HLA class II regulatory factor RFX2; Regulatory factor X 2; regulatory factor X, 2 (influences HLA class II expression); trans-acting regulatory factor 2
Gene Aliases: 5430432H19Rik; RFX2
UniProt ID: (Human) P48378, (Mouse) P48379, (Rat) B2GV50
Entrez Gene ID: (Human) 5990, (Mouse) 19725, (Rat) 301121
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