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Proteintech
RFX4 Polyclonal Antibody
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Product Details
13971-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RFX4 fusion protein Ag5004
Conjugate
Form
Liquid
Concentration
0.35 mg/mL
Amount
52.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: DHLLEEQSPI ESYIEWLDTM VDRCVVKVAA KRQGSLKKVA QQFLLMWSCF GTRVIRDMTL HSAPSFGSFH LIHLMFDDYV LYLLESLHCQ ERANELMRAM KGEGSTAEVR EEIILTEAAA PTPSPVPSFS PAKSATSVEV PPPSSPVSNP SPEYTGLSTT GAMQSYTWSL TYTVTTAAGS PAENSQQLPC MRNTHVPSSS VTHRIPVYPH REEHGYTGSY NYGSYGNQHP HPMQSQYPAL PHDTAISGPL HYAPYHRSSA QYPFNSPTSR MEPCLMSSTP RLHPTPVTPR WPEVPSANTC YTSPSVHSAR YGNSSDMYTP LTTRRNSEYE HMQHFPGFAY INGEASTGWA K
Target Information
This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Regulatory factor X 4; regulatory factor X 4 protein; regulatory factor X, 4 (influences HLA class II expression); Transcription factor RFX4; winged-helix transcription factor RFX4
Gene Aliases: 4933412G19Rik; NYD-sp10; Rfx4; RGD1562092
UniProt ID: (Mouse) Q7TNK1
Entrez Gene ID: (Rat) 500818, (Mouse) 71137
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
DNA binding
protein binding
winged helix/forkhead transcription factor
regulation of transcription from RNA polymerase II promoter
dorsal spinal cord development
telencephalon development
cerebellar cortex morphogenesis
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
forebrain development
midbrain development
cilium assembly
positive regulation of transcription from RNA polymerase II promoter
regulation of protein processing
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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