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Proteintech
RGC32 Polyclonal Antibody
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Product Details
19556-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.55 mg/mL
Amount
82.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
Modulates the activity of cell cycle-specific kinases. Enhances CDK1 activity. May contribute to the regulation of the cell cycle. May inhibit growth of glioma cells by promoting arrest of mitotic progression at the G2/M transition. Fibrogenic factor contributing to the pathogenesis of renal fibrosis through fibroblast activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Regulator of cell cycle RGCC; Response gene to complement 32 protein; RGC-32
Gene Aliases: 1190002H23Rik; bA157L14.2; C13orf15; RGC-32; RGC32; RGCC
UniProt ID: (Human) Q9H4X1, (Mouse) Q9DBX1
Entrez Gene ID: (Human) 28984, (Mouse) 66214
negative regulation of exit from mitosis
negative regulation of cytokine production
positive regulation of cytokine production
negative regulation of endothelial cell proliferation
complement receptor mediated signaling pathway
positive regulation of extracellular matrix constituent secretion
transforming growth factor beta receptor signaling pathway
negative regulation of cell proliferation
positive regulation of gene expression
positive regulation of epithelial to mesenchymal transition
negative regulation of angiogenesis
positive regulation of collagen biosynthetic process
protein kinase B signaling
negative regulation of blood vessel endothelial cell migration
positive regulation of mitotic cell cycle
positive regulation of transcription from RNA polymerase II promoter
positive regulation of stress fiber assembly
regulation of cell cycle
cellular response to hypoxia
fibroblast activation
negative regulation of fibroblast growth factor production
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of extracellular matrix assembly
negative regulation of mitotic cell cycle phase transition
positive regulation of vascular smooth muscle cell proliferation
negative regulation of cell-cell adhesion mediated by cadherin
positive regulation of endothelial cell apoptotic process
G1/S transition of mitotic cell cycle
complement activation
cell cycle
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle
positive regulation of mitotic nuclear division
negative regulation of cytokine secretion
positive regulation of cytokine secretion
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of cell cycle arrest
mitotic cell cycle arrest
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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