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Invitrogen
RGS12 Polyclonal Antibody
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Product Details
PA5-101834
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RGS12(Accession O14924), corresponding to amino acid residues E140-N190.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RGS12.
Target Information
This gene encodes a member of the 'regulator of G protein signaling' (RGS) gene family. The encoded protein may function as a guanosine triphosphatase (GTPase)-activating protein as well as a transcriptional repressor. This protein may play a role in tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their biological nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp761K1617; DKFZp761K1817; Regulator of G-protein signaling 12; regulator of G-protein signalling 12; RGS12; RP11-529E10.1
Gene Aliases: 1200016K18Rik; 4632412M04Rik; AI481290; E130309H11; RGS12
UniProt ID: (Human) O14924, (Rat) O08774, (Mouse) Q8CGE9
Entrez Gene ID: (Human) 6002, (Rat) 54292, (Mouse) 71729
transcription, DNA-templated
signal transduction
regulation of G-protein coupled receptor protein signaling pathway
termination of G-protein coupled receptor signaling pathway
positive regulation of GTPase activity
intracellular signal transduction
negative regulation of G-protein coupled receptor protein signaling pathway
regulation of catalytic activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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