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|Tested species reactivity||Mouse, Human, Rat|
|Host / Isotype||Chicken / IgY|
|Immunogen||Synthetic peptidecorresponding to amino acids 42-99 of RGS13.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-28140 detects RGS13 from rat, mouse, human samples.
PA1-28140 has been successfully used in Western blot applications.
The PA1-28140 immunogen is: Synthetic peptidecorresponding to amino acids 42-99 of RGS13.
The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
MGC17173; regulator of G-protein signaling 13; regulator of G-protein signalling 13; RP11-92K2.1