|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (4 PHEAEKQITGPEEADRPPS 22) of RGS19 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Western Blot (WB)||0.5-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
RGS19 is a member of the RGS protein family, which acts as a GTPase-activating protein (GAPs) for heterotrimeric G proteins, increasing the intrinsic rate of GTP hydrolysis and accelerating signal termination. It is a small protein that contains two potential phosphorylation sites for protein kinase C and seven for casein kinase 2. The gene for RGS19 is localized on human chromosome 20q13.33. RGS19 specifically controls signaling of the Wnt-catenin pathway. The protein is highly expressed in human lung, liver, heart and placenta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.