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Invitrogen
RGS19 Polyclonal Antibody
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FIGURE: 1 / 1
RGS19 Antibody (PA5-78315) in WB
RGS19 Polyclonal Antibody detects RGS19 protein by western blot analysis. A. 30 µg 293T whole cell lysate/extract. B. 30 µg whole cell lysate/extract of human RGS19-transfected 293T cells.12 % SDS-PAGE. RGS19 Polyclonal Antibody (Product # PA5-78315) dilution: 1:10,000.
Product Details
PA5-78315
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human RGS19. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.28 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2736519
Product Specific Information
Positive Control: human RGS19-transfected 293T
Predicted Reactivity: Mouse (87%), Rat (87%), Rhesus Monkey (96%), Bovine (84%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G alpha interacting protein; G protein signalling regulator 19; G-alpha-interacting protein; GAIP; GAIP protein; GS19; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGS19
Gene Aliases: GAIP; GNAI3IP; RGS19; RGSGAIP
UniProt ID: (Human) P49795
Entrez Gene ID: (Human) 10287
regulation of transcription, DNA-templated
autophagy
G-protein coupled receptor signaling pathway
small GTPase mediated signal transduction
cell death
dorsal/ventral axis specification
cell differentiation
regulation of catenin import into nucleus
positive regulation of GTPase activity
cellular response to organic cyclic compound
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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