Invitrogen

RGS19 Polyclonal Antibody

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RGS19 Antibody in Western Blot (WB) — Western blot analysis of RGS19 in A) 293T whole cell lysate, B) whole cell lysate of human RGS19-transfected 293T cells using 30 µg of protein. Samples were separated with 12% SDS-PAGE and incubated with RGS19 polyclonal antibody (Product # PA5-78315) using a dilution of 1:10000.

Product Details

Tested Applications

Dilution

Western Blot (WB)

1:10,000

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human RGS19. The exact sequence is proprietary.

Conjugate

Unconjugated

Form

Liquid

Concentration

0.28 mg/ml

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 20% glycerol

Contains

0.025% Proclin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2736519

Product Specific Information

Positive Control: human RGS19-transfected 293T

Predicted Reactivity: Mouse (87%), Rat (87%), Rhesus Monkey (96%), Bovine (84%)

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Target Information

RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: G alpha interacting protein; G protein signalling regulator 19; G-alpha-interacting protein; GAIP; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGS19; RGSGAIP

Gene Aliases: GAIP; GNAI3IP; RGS19; RGSGAIP

UniProt ID: (Human) P49795

Entrez Gene ID: (Human) 10287

Molecular Function: G-protein modulator enzyme modulator