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Invitrogen
RGS2 Polyclonal Antibody
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Product Details
PA1-41189
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide within amino acid residues 1-50 of human RGS2.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS with 0.2% gelatin
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Suggested positive control: human heart lysate.
Immunogen sequence homology: mouse (86%) and rat (86%).
Target Information
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; GIG31; Regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa; regulator of G-protein signaling protein 2; RGS2; unnamed protein product
Gene Aliases: G0S8; GIG31; GOS8; RGS2
UniProt ID: (Human) P41220, (Rat) Q9JHX0, (Mouse) O08849
Entrez Gene ID: (Human) 5997, (Rat) 84583, (Mouse) 19735
response to amphetamine
regulation of translation
G-protein coupled receptor signaling pathway
spermatogenesis
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of signal transduction
negative regulation of cardiac muscle hypertrophy
positive regulation of neuron projection development
negative regulation of translation
response to ethanol
negative regulation of G-protein coupled receptor protein signaling pathway
negative regulation of JNK cascade
brown fat cell differentiation
relaxation of cardiac muscle
relaxation of vascular smooth muscle
maternal process involved in female pregnancy
positive regulation of cardiac muscle contraction
negative regulation of cell growth involved in cardiac muscle cell development
regulation of adrenergic receptor signaling pathway
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
negative regulation of glycine import across plasma membrane
biological_process
negative regulation of phospholipase activity
positive regulation of microtubule polymerization
termination of G-protein coupled receptor signaling pathway
negative regulation of MAP kinase activity
positive regulation of GTPase activity
negative regulation of cAMP-mediated signaling
cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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