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Invitrogen
RGS2 Polyclonal Antibody
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FIGURE: 1 / 2
RGS2 Antibody (PA5-19644) in ICC/IF
Immunofluorescent staining of SH-SY5Y cells using Product # PA5-19644, anti-RGS2 antibody. The cells were fixed with PFA (4%)for 10 minutes, permabilised TBS-T for 20 minutes and exposed to the primary antibody at a concentration of 1 µg/mL for 1 hour at room temp. A solution of BSA (1%), normal goat serum (10%) and glycine (0.3 M) was used to quench autofluorescence and block non-specific protein-protein interactions. The secondary antibody was a 448 fluorescence conjugated Goat anti-rabbit IgG (green) at a dilution of 1:1000. A WGA- 594 ... View More
Product Details
PA5-19644
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 150 to the C-terminus of Human RGS2.
Conjugate
Form
Liquid
Concentration
0.6 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; GIG31; Regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa; regulator of G-protein signalling 2, 24kDa; RGS2; unnamed protein product
Gene Aliases: G0S8; GIG31; RGS2
UniProt ID: (Human) P41220
Entrez Gene ID: (Human) 5997, (Dog) 488584
response to amphetamine
regulation of translation
G-protein coupled receptor signaling pathway
spermatogenesis
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of signal transduction
negative regulation of cardiac muscle hypertrophy
positive regulation of neuron projection development
negative regulation of translation
response to ethanol
negative regulation of G-protein coupled receptor protein signaling pathway
negative regulation of JNK cascade
brown fat cell differentiation
relaxation of cardiac muscle
relaxation of vascular smooth muscle
maternal process involved in female pregnancy
positive regulation of cardiac muscle contraction
negative regulation of cell growth involved in cardiac muscle cell development
regulation of adrenergic receptor signaling pathway
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
negative regulation of glycine import across plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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