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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 200-400 of human RHBDF1 (NP_071895.3). |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
2.52 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2855703 |
Sequence of this protein is as follows: HRLPRRRKRE SVAKMSFRAA AALMKGRSVR DGTFRRAQRR SFTPASFLEE DTTDFPDELD TSFFAREGIL HEELSTYPDE VFESPSEAAL KDWEKAPEQA DLTGGALDRS ELERSHLMLP LERGWRKQKE GAAAPQPKVR LRQEVVSTAG PRRGQRIAVP VRKLFAREKR PYGLGMVGRL TNRTYRKRID SFVKRQIEDM D
RHBDF1 is a seven-transmembrane protein with a long N-terminal cytoplasmic extension that comprises half of the polypeptide sequence, and is found in the endoplasmic reticulum and Golgi, but not on the cell surface. RHBDF1 has a pivotal role in sustaining growth signals in epithelial cancer cells and thus may serve as a therapeutic target for treating epithelial cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epidermal growth factor receptor related sequence; Epidermal growth factor receptor-related protein; FLJ2235; FLJ22357; gene -89; gene -90; Inactive rhomboid protein 1; iRhom1; rhomboid family 1; Rhomboid family member 1
Gene Aliases: C16ORF8; Dist; Dist1; Egfr-rs; Irhom1; Kiaa4242; mKIAA4242; Rhbdf1
UniProt ID: (Mouse) Q6PIX5, (Rat) Q499S9
Entrez Gene ID: (Mouse) 13650, (Rat) 303008
Molecular Function:
serine protease
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