This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: NVNDFFMRHS VAVMTVRELF EFVTDPSITH ENMDAYLSKA MEIASQRTKE ERSSQDHVDE EVFKRAYIPR TLNEVKNYER DMDIIMKLKE EDMAMNAQQD NILYQTVTGL KKDLSGVQKV PALLENQVEE RTCSDSEDIG SSEC
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 84%.
FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. It may regulate intracellular transport and local transltion of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. FXR1 is required for embryonic and postnatal development of muscle tissue. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RIO kinase 1; Serine/threonine-protein kinase RIO1
Gene Aliases: AD034; bA288G3.1; RIO1; RIOK1; RRP10
UniProt ID: (Human) Q9BRS2
Entrez Gene ID: (Human) 83732