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Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
ELISA (ELISA) |
1:10,000 | - |
Immunoprecipitation (IP) |
1:50-1:250 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic peptide taken within amino acid region 450-500 on human Serine/threonine-protein kinase RIO1 protein. |
Conjugate |
Biotin |
Form |
Liquid |
Concentration |
0.5-1.5 mg/mL |
Purification |
Affinity chromatography |
Storage buffer |
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. It may regulate intracellular transport and local transltion of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. FXR1 is required for embryonic and postnatal development of muscle tissue. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RIO kinase 1; Serine/threonine-protein kinase RIO1
Gene Aliases: AD034; bA288G3.1; RIO1; RIOK1; RRP10
UniProt ID: (Human) Q9BRS2
Entrez Gene ID: (Human) 83732
Molecular Function:
non-receptor serine/threonine protein kinase
protein modifying enzyme
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