Immunogen sequence: FPTFKDIRRE DTLDVEVSAS GYTKEMQADD ELLHPLGPDD KNIETKEGSE FSFSDGEVAE KAEVYRSENE SERNCLEESE GCYCRSSGDP EQIKEDSLSE ESADARSFE
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 67%.
RIOK2 belongs to the protein kinase superfamily; RIO-type Ser/Thr kinase family. Serine/threonine protein kinases, such as RIOK2, phosphorylate the OH group of serine or threonine (which have similar sidechains). Activity of these protein kinases can be regulated by specific events (e.g. DNA damage), as well as numerous chemical signals, including cAMP/cGMP, Diacylglycerol, and Ca2+/calmodulin.
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