|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 322-367 of human RIOK3|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 59 kDa.
Purity is >95% by SDS-PAGE.
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. SUDD, also known as RIOK3 (RIO kinase 3), is a 519 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Expressed in a variety of tissues, SUDD catayzes the ATP-dependent phosphorylation of target proteins, thereby influencing signaling events throughout the cell. SUDD is expressed as two isoforms due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.