RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
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Protein Aliases: CARD-carrying kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta converting enzyme associated kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; growth-inhibiting gene 30; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; Receptor-interacting protein 2; receptor-interacting serine-threonine kinase 2; Receptor-interacting serine/threonine protein kinase 2; Receptor-interacting serine/threonine-protein kinase 2; RIP-2; RIP-like interacting CLARP kinase; RIP-like-interacting CLARP kinase; Tyrosine-protein kinase RIPK2
Gene Aliases: 2210420D18Rik; CARD3; CARDIAK; CCK; D4Bwg0615e; GIG30; RICK; RIP2; RIPK2; UNQ277/PRO314/PRO34092