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|Tested species reactivity||Human, Mouse, Rat,|
|Host / Isotype||Rabbit|
|Immunogen||Synthetic peptide corresponding to the sequence of human RIP2.|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CARD-carrying kinase; CARD-containing IL-1 beta ICE-kinase; CARD-containing interleukin-1 beta-converting enzyme (ICE)-associated kinase; growth-inhibiting gene 30; receptor (TNFRSF)-interacting serine-threonine kinase 2; receptor-interacting protein (RIP)-like interacting caspase-like apoptosis regulatory protein (CLARP) kinase; receptor-interacting protein 2; receptor-interacting serine/threonine-protein kinase 2; RIP-2; tyrosine-protein kinase RIPK2
2210420D18Rik; CARD3; CARDIAK; CCK; D4Bwg0615e; GIG30; RICK; RIP2; RP23-378L22.1; WUGSC:H_RG437L15.1
Protein metabolism and modification Protein modification Protein phosphorylation Signal transduction Cell surface receptor mediated signal transduction Receptor protein serine/threonine kinase signaling pathway Immunity and defense Stress response Apoptosis