This target displays homology in the following species: Cow: 93%; Dog: 92%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rat: 100%
The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation.
Protein Aliases: ankyrin repeat domain-containing protein 3; PKC-delta-interacting protein kinase; protein kinase C-associated kinase; receptor-interacting serine-threonine kinase 4; serine/threonine-protein kinase ANKRD3
Gene Aliases: ANKK2; ANKRD3; DIK; NKRD3; PKK; PPS2; RIP4
Entrez Gene ID: (Human) 54101
Molecular Function: non-receptor serine/threonine protein kinase