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Immunogen sequence: AHTPQVHKNI PSVNAKLKVV KHLIRIKPLK LPQGLPAEEN MSNTCLKSTG ELVVQWHLKP VEQK
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Alternative splicing results in multiple transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p and 12p. Read-through transcription also exists between this gene and the neighboring upstream lipoyltransferase 1 (LIPT1) gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 39S ribosomal protein L28, mitochondrial; 39S ribosomal protein L30, mitochondrial; L28mt; L30mt; Large ribosomal subunit protein uL30m
Gene Aliases: HSPC249; L28MT; L30MT; MRP-L28; MRP-L30; MRPL28; MRPL28M; MRPL30; RPML28
UniProt ID: (Human) Q8TCC3
Entrez Gene ID: (Human) 51263
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