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RNF12 Polyclonal Antibody
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Product Details
BS-9177R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human RNF12, amino acids 550-600.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
RNF12 is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CTD-2530H13.3; DKFZp686N06224; E3 ubiquitin-protein ligase RLIM; E3 ubiquitin-protein ligase RNF12; FLJ25923; FLJ41093; FLJ42887; FLJ45986; Hoxa1 regulated; LIM domain-interacting RING finger protein; MGC15161; R-LIM; Renal carcinoma antigen NY-REN-43; RING finger LIM domain-binding protein; RING finger protein 12; ring zinc finger LIM domain binding protein; ring zinc finger protein NY-REN-43antigen; RING-type E3 ubiquitin transferase RLIM; unnamed protein product
Gene Aliases: AL022832; AW743871; Ha1r; MRX61; NY-REN-43; RLIM; Rlim1; RNF12; TOKAS
UniProt ID: (Human) Q9NVW2, (Mouse) Q9WTV7
Entrez Gene ID: (Human) 51132, (Rat) 317241, (Mouse) 19820
transcription corepressor activity
ubiquitin-protein transferase activity
zinc ion binding
transferase activity
metal ion binding
ubiquitin protein ligase activity
protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
negative regulation of transcription from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
protein ubiquitination
negative regulation of sequence-specific DNA binding transcription factor activity
random inactivation of X chromosome
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of dosage compensation by inactivation of X chromosome
negative regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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