Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: Jurkat.
Predicted reactivity: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%; Yeast: 89%; Zebrafish: 93%.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
RNF12 is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.
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