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Product Details
25260-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RNF123 fusion protein Ag19653
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: RKSYRLTSDA EKSRVTGIVQ EKLLNDYLNR IFSSSEHAPP AATSRKPLNF QNLPEHLDQL LQVDNEEEES QGQVEGRLGP STVVLDHTGG FEGLLLVDDD LLGVIGHSNF GTIRSTTCVY KGKWLYEVLI SSQGLMQIGW CTISCRFNQE EGVGDTHNSY AYDGNRVRKW NVTTTNYGKA WAAGDIVSCL IDLDDGTLSF CLNGVSLGTA FENLSRGLGM AYFPAISLSF KESVAFNFGS RPLRYPVAGY RPLQDPPSAD LVRAQRLLGC FRAVLSVELD PVEGRLLDKE SSKWRLRGQP TVLLTLAHIF HHFAPLLRKV YLVEAVLMSF LLGIVEKGTP TQAQSVV
Target Information
Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase RNF123; Kip1 ubiquitination-promoting complex protein 1; RING finger protein 123
Gene Aliases: FP1477; KPC1; RNF123
UniProt ID: (Human) Q5XPI4
Entrez Gene ID: (Human) 63891
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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