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The protein encoded by RNF135 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis.
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Protein Aliases: E3 ubiquitin-protein ligase RNF135; MGC13061; REUL; RIG-I E3 ubiquitin ligase; RING finger protein 135; RING finger protein leading to RIG-I activation; RING-type E3 ubiquitin transferase RNF135; Riplet
Gene Aliases: L13; MMFD; REUL; Riplet; RNF135
UniProt ID: (Human) Q8IUD6
Entrez Gene ID: (Human) 84282
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