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Proteintech
RNF14 Polyclonal Antibody
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Product Details
26368-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RNF14 Fusion Protein Ag23734 (127-474 aa encoded by BC126185)
Conjugate
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MQFLKEETL AYLNIVSPFE LKIGSQKKVQ RRTAQASPNT ELDFGGAAGS DVDQEEIVDE RAVQDVESLS NLIQEILDFD QAQQIKCFNS KLFLCSICFC EKLGSECMYF LECRHVYCKA CLKDYFEIQI RDGQVQCLNC PEPKCPSVAT PGQVKELVEA ELFARYDRLL LQSSLDLMAD VVYCPRPCCQ LPVMQEPGCT MGICSSCNFA FCTLCRLTYH GVSPCKVTAE KLMDLRNEYL QADEANKRLL DQRYGKRVIQ KALEEMESKE WLEKNSKSCP CCGTPIEKLD GCNKMTCTGC MQYFCWICMG SLSRANPYKH FNDPGSPCFN RLFYAVDVDD DIWEDEVED (127-474 aa encoded by BC126185)
Target Information
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Five alternatively spliced transcript variants encoding two distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: androgen receptor associated protein 54; Androgen receptor-associated protein 54; E3 ubiquitin-protein ligase RNF14; HFB30; RING finger protein 14
Gene Aliases: ARA54; HFB30; HRIHFB2038; RNF14; TRIAD2
UniProt ID: (Human) Q9UBS8
Entrez Gene ID: (Human) 9604
protein polyubiquitination
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
signal transduction
protein ubiquitination
androgen receptor signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
positive regulation of transcription, DNA-templated
regulation of androgen receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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