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          • Primary Antibodies ›
          • RNF17 Antibodies

          Proteintech

          RNF17 Polyclonal Antibody

          View all (4) RNF17 antibodies

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          Cite RNF17 Polyclonal Antibody

          • Antibody Testing Data (5)
          RNF17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          RNF17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          RNF17 Antibody (24302-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using (Product # 24302-1-AP) (RNF17 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          RNF17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RNF17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RNF17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RNF17 Antibody in Western Blot (WB)
          RNF17 Antibody in Immunoprecipitation (IP)
          RNF17 Polyclonal Antibody

          Product Details

          24302-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          RNF17 Fusion Protein Ag20144 (296-652 aa encoded by BC146822)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.62 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: ICMFNNMGK IEFRDSTKCY PQENEIRQNV QKKYNNKKEL SCYDTYPPLE KKKVDMSVLT SEAPPPPLQP ETNDVHLEAK NFQPQKDVAT ASPKTIAVLP QMGSSPDVII EEIIEDNVES SAELVFVSHV IDPCHFYIRK YSQIKDAKVL EKKVNEFCNR SSHLDPSDIL ELGARIFVSS IKNGMWCRGT ITELIPIEGR NTRKPCSPTR LFVHEVALIQ IFMVDFGNSE VLIVTGVVDT HVRPEHSAKQ HIALNDLCLV LRKSEPYTEG LLKDIQPLAQ PCSLKDIVPQ NSNEGWEEEA KVEFLKMVNN KAVSMKVFRE EDGVLIVDLQ KPPPNKISSD MPVSLRDALV FMELAKRT (296-652 aa encoded by BC146822)

          Target Information

          RNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is specifically expressed in testis. The RING finger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Mad member-interacting protein 2; Max dimerization protein member-interacting protein 2; Mmip-2; RING finger protein 17; spermatogenesis associated 23; tudor domain containing 4; Tudor domain-containing protein 4

          View more View less

          Gene Aliases: MMIP-2; Mmip2; RNF17; SPATA23; TDRD4

          View more View less

          UniProt ID: (Human) Q9BXT8, (Mouse) Q99MV7

          View more View less

          Entrez Gene ID: (Human) 56163, (Mouse) 30054

          View more View less

          Function(s)
          zinc ion binding protein homodimerization activity metal ion binding
          Process(es)
          multicellular organism development spermatogenesis spermatid development cell differentiation
          It has to be done as per old AB suggested Products section.
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