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Product Details
24302-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RNF17 Fusion Protein Ag20144 (296-652 aa encoded by BC146822)
Conjugate
Form
Liquid
Concentration
0.62 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ICMFNNMGK IEFRDSTKCY PQENEIRQNV QKKYNNKKEL SCYDTYPPLE KKKVDMSVLT SEAPPPPLQP ETNDVHLEAK NFQPQKDVAT ASPKTIAVLP QMGSSPDVII EEIIEDNVES SAELVFVSHV IDPCHFYIRK YSQIKDAKVL EKKVNEFCNR SSHLDPSDIL ELGARIFVSS IKNGMWCRGT ITELIPIEGR NTRKPCSPTR LFVHEVALIQ IFMVDFGNSE VLIVTGVVDT HVRPEHSAKQ HIALNDLCLV LRKSEPYTEG LLKDIQPLAQ PCSLKDIVPQ NSNEGWEEEA KVEFLKMVNN KAVSMKVFRE EDGVLIVDLQ KPPPNKISSD MPVSLRDALV FMELAKRT (296-652 aa encoded by BC146822)
Target Information
RNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is specifically expressed in testis. The RING finger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mad member-interacting protein 2; Max dimerization protein member-interacting protein 2; Mmip-2; RING finger protein 17; spermatogenesis associated 23; tudor domain containing 4; Tudor domain-containing protein 4
Gene Aliases: MMIP-2; Mmip2; RNF17; SPATA23; TDRD4
UniProt ID: (Human) Q9BXT8, (Mouse) Q99MV7
Entrez Gene ID: (Human) 56163, (Mouse) 30054
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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