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Product Details
PA5-65333
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human RNF207. Recombinant protein control fragment (Product #RP-104755).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663775
Product Specific Information
Immunogen sequence: GSPVQKPTLHR SISTKVLLAE GENTPFAEHC RHYEDSYRHL QAEMQSLKDQ VQELHRDLTK HHSLIKAEIM GDVLHKSL
Highest antigen sequence identity to the following orthologs - mouse 85%, rat 86%.
Target Information
Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel KCNH2/HERG, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RING finger protein 207
Gene Aliases: C1orf188; RNF207
UniProt ID: (Human) Q6ZRF8
Entrez Gene ID: (Human) 388591
positive regulation of gene expression
regulation of cardiac muscle contraction
cell-cell signaling involved in cardiac conduction
regulation of heart looping
positive regulation of delayed rectifier potassium channel activity
positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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