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Proteintech
RNF220 Polyclonal Antibody
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Product Details
32482-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RNF220 fusion protein Ag36190
Conjugate
Form
Liquid
Concentration
400 µg/mL
Amount
60 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Sequence of this protein is as follows: SKNSLLKDAM APGTPKSLLL SASIKREGES PTASPHSSAT DDLHHSDRYQ TFLRVRANRQ TRLNARIGKM KRRKQDEGQR EGSCMAEDDA VDIEHENNNR FEEYEWCGQK RIRATTLLEG GFRGSGFIMC SGKENPDSDA DLDVDGDDTL EYGKPQYTEA DVIPCTGEEP GEAKEREALR GAVLNGGPPS TRITPEFSKW ASDEMPSTSN GESSKQEAMQ KTCKNSDIEK ITEDSAVTTF EALKARVREL ERQLSRGDRY KCLICMDSYS MPLTSIQCWH VHCEECWLRT LGAKKLCPQC NTITAPGDLR RIYL
Target Information
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase RNF220; RING finger protein 220; RING-type E3 ubiquitin transferase RNF220; unnamed protein product
Gene Aliases: 4732477A13; 4931406I20Rik; 5730503K05Rik; AV302541; C1orf164; HLD23; RNF220
UniProt ID: (Human) Q5VTB9, (Mouse) Q6PDX6
Entrez Gene ID: (Human) 55182, (Rat) 500532, (Mouse) 66743
ubiquitin-protein transferase activity
protein binding
beta-catenin binding
zinc ion binding
transferase activity
metal ion binding
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
protein ubiquitination
protein autoubiquitination
positive regulation of canonical Wnt signaling pathway
noradrenergic neuron development
protein monoubiquitination
dorsal/ventral neural tube patterning
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of postsynaptic neurotransmitter receptor internalization
regulation of transcription regulatory region DNA binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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