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Immunogen sequence: VVFSGQHLPV CSVPPPMLQA CSVQHLPVPY AAFPPLISSD PFLIHPPHLS PHHPPHLPPP GQFVPFQTQQ SRSPLQRIEN EVELLGEHLP VGGFTYPPSA HPPTLPPSAP L
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.
RNF38 is a protein with a coiled-coil motif and a RING-H2 motif (C3H2C2) at its carboxy-terminus. The RING motif is a zinc-binding domain found in a large set of proteins playing roles in diverse cellular processes including oncogenesis, development, signal transduction, and apoptosis. This gene encodes a protein with a coiled-coil motif and a RING-H2 motif (C3H2C2) at its carboxy-terminus. The RING motif is a zinc-binding domain found in a large set of proteins playing roles in diverse cellular processes including oncogenesis, development, signal transduction, and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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Protein Aliases: E3 ubiquitin-protein ligase RNF38; FLJ21343; RING finger protein 38; RING-type E3 ubiquitin transferase RNF38
Gene Aliases: RNF38
UniProt ID: (Human) Q9H0F5
Entrez Gene ID: (Human) 152006
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