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The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.
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Protein Aliases: E3 ubiquitin-protein ligase RNF5; HsRma1; protein G16; Ram1 homolog; RING finger protein 5; ring finger protein 5, E3 ubiquitin protein ligase
Gene Aliases: G16; NG2; RING5; RMA1; RNF5
UniProt ID: (Human) Q99942
Entrez Gene ID: (Human) 6048
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