Proteintech

RNMTL1 Polyclonal Antibody

View all (8) RNMTL1 antibodies

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RNMTL1 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 14707-1-AP (RNMTL1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

RNMTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver using 14707-1-AP (RNMTL1 antibody) at dilution of 1:100 (under 40x lens).

RNMTL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver using 14707-1-AP (RNMTL1 antibody) at dilution of 1:100 (under 10x lens).

RNMTL1 Antibody in Western Blot (WB) — HEK-293 cells were subjected to SDS PAGE followed by western blot with 14707-1-AP (RNMTL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

RNMTL1 Antibody in Western Blot (WB) — HeLa cells were subjected to SDS PAGE followed by western blot with 14707-1-AP (RNMTL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

14707-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:1,000-1:5,000	View 1 publication 1 publication
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:50-1:500	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	RNMTL1 Fusion Protein Ag6399 (1-420 aa encoded by BC050614) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.4 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MAALVRPSR FVVRPLLQVV QAWDLDARRW VRALRRSPVK VVFPSGEVVE QKRAPGKQPR KAPSEASAQE QREKQPLEES ASRAPSTWEE SGLRYDKAYP GDRRLSSVMT IVKSRPFREK QGKILLEGRR LISDALKAGA VPKMFFFSRL EYLKELPVDK LKGVSLIKVK FEDIKDWSDL VTPQGVMGIF AKPDHVKMTY PKTQLQHSLP LLLICDNLRD PGNLGTILRS AAGAGCSKVL LTKGCVDAWE PKVLRAGMGA HFRMPIINNL EWETVPNYLP PDTRVYVADN CGLYAQAEMS NKASDHGWVC DQRVMKFHKY EEEEDVETGA SQDWLPHVEV QSYDSDWTEA PAAVVIGGET YGVSLESLQL AESTGGKRLL IPVVPGVDSL NSAMAASILL FEGKRQLRGR AEDLSRDRSY H (1-420 aa encoded by BC050614)

Target Information

The RNA methyltransferase like 1 gene (RNMTL1) is one of thirteen newly discovered genes within a 116 Kb segment of the chromosome 17p13.3, which suffers from a high frequent loss of heterozygosity in human hepatocellular carcinoma. Its amino acid sequence was identified a high conserved region with methylases from various microorganisms, suggesting to have function to transfer methyl group to rRNA molecule.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Mitochondrial ribosomal RNA (rRNA) methyltransferase family members are positioned to modify nascent rRNA in foci near the mitochondrial DNA nucleoid.

The Journal of biological chemistry

Lee KW,Okot-Kotber C,LaComb JF,Bogenhagen DF

Fri Oct 25 00:00:00 EDT 2013

Mitochondrial ribosomal RNA (rRNA) methyltransferase family members are positioned to modify nascent rRNA in foci near the mitochondrial DNA nucleoid.

The Journal of biological chemistry

Lee KW,Okot-Kotber C,LaComb JF,Bogenhagen DF

Fri Oct 25 00:00:00 EDT 2013

Bioinformatics

Protein Aliases: 16S rRNA (guanosine(1370)-2'-O)-methyltransferase; 16S rRNA [Gm1370] 2'-O-methyltransferase; putative RNA methyltransferase; RNA methyltransferase like 1; RNA methyltransferase-like protein 1; rRNA methyltransferase 3, mitochondrial

Gene Aliases: 4833420N02Rik; AI255153; HC90; MRM3; RGD1309077; RMTL1; RNMTL1

UniProt ID: (Human) Q9HC36, (Mouse) Q5ND52

Entrez Gene ID: (Human) 55178, (Mouse) 67390, (Rat) 360569

Molecular Function: RNA methyltransferase

RNA methylation rRNA processing RNA processing biological_process methylation

Process(es)

RNA binding protein binding methyltransferase activity RNA methyltransferase activity poly(A) RNA binding rRNA (adenine-N6,N6-)-dimethyltransferase activity protein C-terminal carboxyl O-methyltransferase activity tRNA (guanine-N2-)-methyltransferase activity C-methyltransferase activity N-methyltransferase activity O-methyltransferase activity S-methyltransferase activity mRNA methyltransferase activity tRNA methyltransferase activity protein methyltransferase activity 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity rRNA methyltransferase activity rRNA (uridine-2'-O-)-methyltransferase activity rRNA (adenine-N6-)-methyltransferase activity DNA-methyltransferase activity tRNA (guanine-N1-)-methyltransferase activity rRNA (cytosine-C5-)-methyltransferase activity selenocysteine methyltransferase activity arginine N-methyltransferase activity protein-arginine N-methyltransferase activity lysine N-methyltransferase activity protein-lysine N-methyltransferase activity tRNA (uracil) methyltransferase activity tRNA (guanine) methyltransferase activity tRNA (adenine) methyltransferase activity tRNA (cytosine) methyltransferase activity tRNA (cytosine-5-)-methyltransferase activity tRNA (adenine-N1-)-methyltransferase activity rRNA (adenine) methyltransferase activity rRNA (cytosine) methyltransferase activity rRNA (guanine) methyltransferase activity rRNA (uridine) methyltransferase activity transferase activity protein C-terminal leucine carboxyl O-methyltransferase activity 1-phenanthrol methyltransferase activity protein-arginine N5-methyltransferase activity methylarsonite methyltransferase activity dimethylarsinite methyltransferase activity 4,5-dihydroxybenzo(a)pyrene methyltransferase activity 1-hydroxypyrene methyltransferase activity 1-hydroxy-6-methoxypyrene methyltransferase activity demethylmenaquinone methyltransferase activity cobalt-precorrin-6B C5-methyltransferase activity cobalt-precorrin-7 C15-methyltransferase activity cobalt-precorrin-5B C1-methyltransferase activity cobalt-precorrin-3 C17-methyltransferase activity dimethylamine methyltransferase activity hydroxyneurosporene-O-methyltransferase activity tRNA (adenine-57, 58-N(1)-) methyltransferase activity methylamine-specific methylcobalamin:coenzyme M methyltransferase activity trimethylamine methyltransferase activity methanol-specific methylcobalamin:coenzyme M methyltransferase activity monomethylamine methyltransferase activity P-methyltransferase activity Se-methyltransferase activity 2-phytyl-1,4-naphthoquinone methyltransferase activity tRNA (uracil-2'-O-)-methyltransferase activity tRNA (cytosine-2'-O-)-methyltransferase activity phosphomethylethanolamine N-methyltransferase activity tRNA (cytosine-3-)-methyltransferase activity rRNA (cytosine-2'-O-)-methyltransferase activity rRNA (cytosine-N4-)-methyltransferase activity trihydroxyferuloyl spermidine O-methyltransferase activity