Keep as concentrated solution.
Positive Control: HeLa, HepG2, Molt-4, mouse brain, NIH-3T3.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
RORA is a receptor for retinoic acid belonging to the NR1 subfamily of nuclear hormone receptors with a nuclear receptor DNA binding domain. RORA binds either as a monomer or as a homodimer to the retinoic acid response element and thus regulates gene expression and also controls cell function. Though the exact function of RORA is yet unknown, it interacts with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, NM23-1, the product of a tumor metastasis suppressor candidate gene, CDK7, NCOA3 and NCOA6 coactivators. It is found to express in mesenchymal stem cells derived from bone marrow and are known to act by direct modulation of a bone matrix component. It is widely expressed in most of the tissues. Chromosomal aberrations involving RORA may be a cause of acute promyelocytic leukemia (APL).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZp686M2414 antibody; MGC119326 antibody; MGC119329 antibody; NR1F1 antibody; Nuclear receptor ROR-alpha; nuclear receptor ROR-alpha antibody; Nuclear receptor RZR-alpha; nuclear receptor RZR-alpha antibody; Nuclear receptor subfamily 1 group F member 1; nuclear receptor subfamily 1 group F member 1 antibody; RAR-related orphan receptor A; RAR-related orphan receptor A antibody; retinoic acid receptor-related orphan receptor alpha; retinoic acid receptor-related orphan receptor alpha antibody; retinoid-related orphan receptor alpha; retinoid-related orphan receptor alpha antibody; Retinoid-related orphan receptor-alpha; ROR-alpha; ROR-alpha antibody; ROR1 antibody; ROR2 antibody; ROR3 antibody; RORA antibody; RZR-ALPHA antibody; RZRA antibody; thyroid hormone nuclear receptor alpha variant 4; thyroid hormone nuclear receptor alpha variant 4 antibody; transcription factor RZR-alpha; transcription factor RZR-alpha antibody
Gene Aliases: 9530021D13Rik; nmf267; NR1F1; ROR1; ROR2; ROR3; RORA; RZR-ALPHA; RZRA; sg; staggerer; tmgc26