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RPA Interacting Protein Polyclonal Antibody
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FIGURE: 1 / 2
RPA Interacting Protein Antibody (600-401-EB8) in IHC (P)
Immunohistochemistry of RPA Interacting Protein antibody. Tissue: mouse stomach tissue. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: RPAI antibody at 2.5 µg/mL for 1 hr at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: RPAI is nuclear and occasionally cytoplasmic. Staining: RPAI as precipitated red si... View More
Product Details
600-401-EB8
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-RPA IP antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide from near the C-terminus of human RPA IP.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hRIP; importin; nuclear transporter; RAP interaction protein; RAP interaction protein alpha; RPA interacting protein delta 2; RPA interacting protein epsilon; RPA-interacting protein; unnamed protein product
Gene Aliases: 2400006N03Rik; HRIP; RGD1308492; RIP; RPAIN
UniProt ID: (Human) Q86UA6, (Mouse) Q9CWY9, (Rat) Q4G2Y1
Entrez Gene ID: (Human) 84268, (Mouse) 69723, (Rat) 287463
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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