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Invitrogen
RPGRIP1L Polyclonal Antibody
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FIGURE: 1 / 6
RPGRIP1L Antibody (PA5-100049) in ICC/IF
Immunofluorescent analysis of RPGRIP1L in HepG2. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with RPGRIP1L polyclonal antibody (Product # PA5-100049) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Product Details
PA5-100049
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RPGRIP1L(Accession Q68CZ1), corresponding to amino acid residues E72-L122.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RPGRIP1L.
Target Information
The protein encoded by this gene can localize to the basal body-centrosome complex or to primary cilia and centrosomes in ciliated cells. The encoded protein has been found to interact with nephrocystin-4. Defects in this gene are a cause of Joubert syndrome type 7 and Meckel syndrome type 5. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686C0668; fantom; fantom homolog; Nephrocystin-8; Protein fantom; protein phosphatase 1, regulatory subunit 134; RPGR-interacting protein 1-like protein; RPGRIP1-like; RPGRIP1-like protein
Gene Aliases: 1700047E16Rik; 4931437C01; CORS3; FTM; JBTS7; KIAA1005; MKS5; NPHP8; PPP1R134; RGD1311099; RPGRIP1L
UniProt ID: (Human) Q68CZ1, (Mouse) Q8CG73
Entrez Gene ID: (Human) 23322, (Mouse) 244585, (Rat) 307724
in utero embryonic development
establishment of planar polarity
kidney development
liver development
establishment or maintenance of cell polarity
determination of left/right symmetry
regulation of smoothened signaling pathway
neural tube patterning
cerebellum development
lateral ventricle development
olfactory bulb development
corpus callosum development
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
cilium assembly
camera-type eye development
nose development
negative regulation of G-protein coupled receptor protein signaling pathway
pericardium development
cochlea development
brain development
telencephalon development
limb morphogenesis
cilium morphogenesis
head development
biological_process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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