|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 1 and 178 of Human RPL15|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27543 targets RPL15 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-27543 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 178 of Human RPL15.
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L15E family of ribosomal proteins. It is located in the cytoplasm. This gene shares sequence similarity with the yeast ribosomal protein YL10 gene. Although this gene has been referred to as RPL10, its official symbol is RPL15. This gene has been shown to be overexpressed in some esophageal tumors compared to normal matched tissues. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Protein Aliases: 60S ribosomal protein L15; EC45; Large ribosomal subunit protein eL15; RPL10; RPLY10; RPYL10
Gene Aliases: DBA12; EC45; L15; RPL10; RPL15; RPLY10; RPYL10; TCBAP0781
UniProt ID: (Human) P61313
Entrez Gene ID: (Human) 6138