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Invitrogen
RPL22/RPL22L1 Polyclonal Antibody
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FIGURE: 1 / 3
RPL22/RPL22L1 Antibody (PA5-104112) in IHC (P)
Immunohistochemistry analysis of RPL22/RPL22L1 in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with RPL22/RPL22L1 polyclonal antibody (Product # PA5-104112) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-104112
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RPL22L1(Accession Q6P5R6), corresponding to amino acid residues I57-R107.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RPL22/L1.
Target Information
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60S ribosomal protein L22; 60S ribosomal protein L22-like 1; EAP; EBER-associated protein; Epstein-Barr virus small RNA-associated protein; Epstein-Barr-encoded RNA-associated protein; heparin-binding protein 15; Heparin-binding protein HBp15; Large ribosomal subunit protein eL22; Large ribosomal subunit protein eL22-like 1; Ribosomal protein eL22-like; Ribosomal protein eL22-like 1; RPL22; unnamed protein product
Gene Aliases: 2700038K18Rik; 3110001N18Rik; AU041196; EAP; eL22; HBP15; HBP15/L22; L22; RGD1309517; RPL22; RPL22L1
UniProt ID: (Human) P35268, (Human) Q6P5R6, (Rat) P47198, (Mouse) P67984, (Mouse) Q9D7S7
Entrez Gene ID: (Human) 6146, (Human) 200916, (Rat) 81768, (Mouse) 19934, (Mouse) 68028, (Rat) 361923
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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