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Product Details
H00006176-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RPLP1 (NP_000994.1, 1 a.a. approximately 114 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MASVSELACI YSALILHDDE VTVTEDKINA LIKAAGVNVE PFWPGLFAKA LANVNIGSLI CNVGAGGPAP AAGAAPAGGP APSTAAAPAE EKKVEAKKEE SEESDDDMGF GLFD
Target Information
Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein LP1 (ribosomal protein, large, P1), also known as 60S acidic ribosomal protein P1, RPP1 or RPLP1, is a 114 amino acid acidic protein that belongs to the ribosomal protein L12P family. A key component during the elongation step of protein synthesis, Ribosomal Protein LP1 forms a pentameric complex (in conjunction with LP2 and LP0) that regulates ribosome assembly and plays a role in translation initiation. Like other mammalian ribosomal proteins, Ribosomal Protein LP1 exists as multiple processed pseudogenes that are found throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60S acidic ribosomal protein P1; acidic ribosomal phosphoprotein P1; L RPP1; Large ribosomal subunit protein P1; ribosomal protein, large, P1
Gene Aliases: LP1; P1; RPLP1; RPP1; RRP1
UniProt ID: (Human) P05386
Entrez Gene ID: (Human) 6176
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
cytoplasmic translation
rRNA processing
translation
translational initiation
translational elongation
SRP-dependent cotranslational protein targeting to membrane
viral transcription
activation of protein kinase activity
positive regulation of protein kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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