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Invitrogen
RPLP1 Polyclonal Antibody
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FIGURE: 1 / 2
RPLP1 Antibody (PA5-103540) in ICC/IF
Immunofluorescent analysis of RPLP1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and RPLP1 polyclonal antibody (Product # PA5-103540) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-103540
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RPLP1(Accession P05386), corresponding to amino acid residues G36-A86.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RPLP1.
Target Information
Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein LP1 (ribosomal protein, large, P1), also known as 60S acidic ribosomal protein P1, RPP1 or RPLP1, is a 114 amino acid acidic protein that belongs to the ribosomal protein L12P family. A key component during the elongation step of protein synthesis, Ribosomal Protein LP1 forms a pentameric complex (in conjunction with LP2 and LP0) that regulates ribosome assembly and plays a role in translation initiation. Like other mammalian ribosomal proteins, Ribosomal Protein LP1 exists as multiple processed pseudogenes that are found throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60S acidic ribosomal protein P1; acidic ribosomal phosphoprotein P1; L RPP1; Large ribosomal subunit protein P1; ribosomal protein, large, P1
Gene Aliases: 2410042H16Rik; Arpp1; C430017H15Rik; LP1; P1; RPLP1; RPP1; RRP1
UniProt ID: (Human) P05386, (Mouse) P47955, (Rat) P19944
Entrez Gene ID: (Human) 6176, (Mouse) 56040, (Rat) 140661
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
cytoplasmic translation
rRNA processing
translation
translational initiation
translational elongation
SRP-dependent cotranslational protein targeting to membrane
viral transcription
activation of protein kinase activity
positive regulation of protein kinase activity
regulation of translation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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