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Product Details
15085-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RPS19 Fusion Protein Ag7164 (1-145 aa encoded by BC000023)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPGVTVKDV NQQEFVRALA AFLKKSGKLK VPEWVDTVKL AKHKELAPYD ENWFYTRAAS TARHLYLRGG AGVGSMTKIY GGRQRNGVMP SHFSRGSKSV ARRVLQALEG LKMVEKDQDG GRKLTPQGQR DLDRIAGQVA AANKKH (1-145 aa encoded by B C000023)
Target Information
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia, a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 40S ribosomal protein S19; HGNC:10402; Small ribosomal subunit protein eS19
Gene Aliases: DBA; DBA1; Dsk3; RPS19; S19
UniProt ID: (Human) P39019, (Rat) P17074, (Mouse) Q9CZX8
Entrez Gene ID: (Human) 6223, (Rat) 29287, (Mouse) 20085
ribosomal small subunit assembly
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
monocyte chemotaxis
rRNA processing
translation
translational initiation
SRP-dependent cotranslational protein targeting to membrane
nucleolus organization
Notch signaling pathway
response to extracellular stimulus
viral transcription
erythrocyte differentiation
maturation of SSU-rRNA
ribosomal small subunit biogenesis
protein tetramerization
positive regulation of cellular component movement
positive regulation of respiratory burst involved in inflammatory response
negative regulation of respiratory burst involved in inflammatory response
biological_process
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